LOS ANGELES — New research from Keck Medicine of the University of Southern California (USC) bolsters evidence that exposure to tobacco smoke and near-roadway air pollution contribute to the development of obesity.
The study, to be posted online Wednesday, Nov. 12, 2014 in Environmental Health Perspectives, (click here) shows increased weight gain during adolescence in children exposed to secondhand tobacco smoke or near-roadway air pollution, compared to children with no exposure to either of these air pollutants. The study is one of the first to look at the combined effects on body mass index of exposure to both near-roadway air pollution and tobacco smoke. The effects were substantially greater in children exposed to both air pollutant mixtures than to either alone.
“Vehicle miles traveled, exposure to some components of the near-roadway air pollutant mixture, and near roadway residential development have increased across the United States over the last several decades corresponding to the epidemic of childhood obesity,” said Rob McConnell, M.D., professor of preventive medicine, Keck School of Medicine of USC and lead author on the study. “The potential for near-roadway air pollution to be among several factors contributing to the epidemic of obesity merits further investigation.”The research builds on previous studies showing that exposure to secondhand smoke and particulate air pollution cause heart and lung disease.
Childhood obesity has doubled in children and quadrupled in adolescents in the past 30 years, according to the Centers for Disease Control and Prevention (CDC). Obese youth are more likely to suffer from health challenges, including high cholesterol, high blood pressure, diabetes, bone and joint problems, social stigmatization and self-esteem problems. Obesity for children is defined by the CDC as a BMI at or above the 95th percentile for children of the same age and sex.
The researchers estimated near-roadway pollution exposure, taking into account traffic volume, how close the children lived to roadways and predominant wind direction. At study entry, a parent-completed questionnaire was used to determine lifetime tobacco smoke exposure.
“Further research is needed to determine if our findings can be replicated in other populations,” McConnell said, “and to assess both the potential contribution of combustion sources to the epidemic of obesity and the potential impact of interventions to reduce exposure.”
Funding for the research comes from the National Institutes of Health (grants P01ES022845, P30ES007048, P01ES009581, P01ES011627, P50 CA180905, R01ES016535, R01HD061968 and R03ES014046), the Environmental Protection Agency (grants RD83544101, R826708 and RD831861) and the Hastings Foundation.
McConnell, R., Shen, E., Gilliland, F.D., Jerrett, M., Wolch, J., Chang, C., Lurmann, F., Berhane, K. (2014). A Longitudinal Cohort Study of Body Mass Index and Childhood Exposure to Secondhand Tobacco Smoke and Air Pollution: The Southern California Children’s Health Study. Environmental Health Perspectives. Published online Nov. 12, 2014.
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This news release was prepared by USC Health Sciences Public Relations & Marketing and the Division of Environmental Health.