BY Leigh Hopper, in USC News, NOVEMBER 20, 2019
Women in their 70s and 80s who were exposed to fine particle pollution had declines in memory and physical brain changes that were not seen in women who breathed cleaner air.
Women in their 70s and 80s who were exposed to higher levels of air pollution experienced greater declines in memory and more Alzheimer’s-like brain atrophy than their counterparts who breathed cleaner air, according to USC researchers.
The findings of the nationwide study, published Wednesday in the journal Brain, touch on the renewed interest in preventing Alzheimer’s disease by reducing risk as well as hint at a potential disease mechanism. Alzheimer’s is the sixth leading cause of death in the United States, and there’s currently no cure or treatment.
“This is the first study to really show, in a statistical model, that air pollution was associated with changes in people’s brains and that those changes were then connected with declines in memory performance,” said Andrew Petkus, assistant professor of clinical neurology at the Keck School of Medicine at USC. “Our hope is that, by better understanding the underlying brain changes caused by air pollution, researchers will be able to develop interventions to help people with or at risk for cognitive decline.”
Fine particles, also called PM2.5 particles, are about 1/30th the width of a human hair. They come from traffic exhaust, smoke and dust and their tiny size allows them to remain airborne for long periods, get inside buildings, be inhaled easily, and reach and accumulate in the brain. Fine particle pollution is associated with asthma, cardiovascular disease, lung disease and premature death.
Previous research has suggested that fine particle pollution exposure increases the risk of Alzheimer’s disease and related dementias. What scientists haven’t known is whether PM2.5 alters brain structure and accelerates memory decline.Continue reading “NEW RESEARCH connects air pollution, memory problems and Alzheimer’s-like brain changes”